Clinical Trials

An open-label randomised Phase 3 study of MK - 2870 by itself and in combination with Keytruda versus a treatment of physicians choice in participants with HR+/HER2- unresectable, locally advanced or metastatic breast cancer.
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The PAM study is designed to explore the effects of combining a talk therapy called meaning-centred psychotherapy with repeated microdoses (very small doses) of LSD on psychological well-being and cancer-related distress.
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This study will evaluate the safety and efficacy of targeted therapies or immunotherapy in participants with have inoperable tumours that have a genetic mutation.
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This study aims to find out if receiving intravenous iron ferric carboxymaltose will reduce the incidence of anaemia while patients are receiving adjuvant chemotherapy for breast cancer, and whether this is associated with an improvement in quality of life and exercise tolerance.
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This trial is evaluating a new online service for managing self-reported symptoms by people with advanced breast cancer.
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A randomised clinical trial of adjuvant radiation therapy versus observation following breast conserving surgery and endocrine therapy in patients with molecularly characterised luminal A low risk early breast cancer.
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New Zealand Clinical Research is calling for male volunteers in Auckland and Christchurch to participate in two large trials looking at potential new treatments for breast cancer.
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This study will compare if StrataXRT gel is adequate compared with Mepitel film in decreasing the number of women who develop radiation-induced skin reactions during or immediately after radiation for breast cancer.
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The New Zealand Familial Breast Cancer Study commenced in 2013 with the key goal of better-understanding DNA sequence changes in genes that alter the risk of developing breast cancer
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This is an observational cohort study of toxicity in female patients treated for early breast cancer with Adriamycin and Cyclophosphamide chemotherapy.
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This study is assessing the benefits of prescribed exercise in clinical populations, including people with breast cancer.
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This study aims to reduce inflammation in post-menopausal women with breast cancer through the use of asprin.
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A phase one clinical study to test safety and how well the oral drug ZN-A-1041 works by itself, or with another approved drug (PHESGO of Enhertu). As this is a phase one study, the sponsor will also be looking at how well ZN-A-1041 is tolerated and how it interacts within the body.
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This study looks at using a magnetic tracer verses a standard technique for sentinel node biopsy in breast cancer.
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This study will introduce participants to a supervised, personalised exercise programme from point-of-diagnosis through to week 12 of chemotherapy in individuals receiving treatment for early-stage breast cancer.
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The primary purpose of this study is to investigate whether it is effective and feasible to treat post cancer related fatigue (CRF) using acupuncture.
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The primary purpose of this study is to develop and evaluate a new low literacy decision aid relating to fertility preservation for younger women with early stage breast cancer.
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The purpose of this study is to see if a program of manual drainage and use of a compression bra can improve outcomes for breast cancer patients experiencing post-treatment oedema (accumulation of fluid under the skin).
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BRCA-P is an international breast cancer prevention clinical trial open to women with a confirmed BRCA1 gene mutation who have not had a diagnosis of breast cancer.
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This trial will investigate if treatment with a PI3K inhibitor (alpelisib), in combination with fulvestrant, will improve outcomes for patients with metastatic breast cancer when compared with standard treatment.
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This study aims to assess the efficacy and safety of cryotherapy in preventing CIPN in patients receiving taxanes for breast or gynaecological cancer.
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This study aims to find out if the combination of anti-HER2 therapy with PD-L1 inhibitor and CTLA4 inhibitor will reactivate anti-tumour immune response and improve clinical outcomes in trastuzumab-resistant, advanced HER2+ breast cancer.
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The purpose of this study is to see if a handheld imaging device (MEprobe) can accurately detect the microscopic presence of cancer in breast surgery patients.
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Lifepool is a research resource for study into breast cancer and women's health. It aims to recruit 100,000 Australian women. This will establish one of the largest cohorts in the world, providing research tools to answer critical questions about breast cancer. Lifepool aims to gather information on health and lifestyle, mammogram data and asks permission to track the health of each participant through linkage with other health databases.
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This study will investigate the feasibility of using oestradiol vaginal tablets for women on adjuvant aromatase inhibitors for breast cancer.
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This study is investigating the combination of palbociclib, letrozole and venetoclax in ER and BCL-2 positive locally advanced or metastatic breast cancer.
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This interventional study will look at the effect of self-directed physical activity and motivational interviewing on quality of life, psychological health and immune outcomes in female breast cancer survivors
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This study will investigate whether delivering radiation therapy while patients are in a prone position can help minimise skin toxicities ahead of surgery.
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The purpose of this study is to investigate whether it is possible for blood samples to be used to monitor whether the correct dose of cancer medicines are being provided to patients.
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This trial is investigating the efficacy and feasibility of a personalised risk assessment for breast and ovarian cancer, through offering a polygenic risk score.
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This trial is investigating the efficacy of providing neuropsychological feedback in addressing self-reported cognitive impairment in breast cancer survivors.
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This study will assess the safety and effectiveness of an investigational agent (MSH2TR) used to detect lymph node spread of cancer in patients with HER2+ breast cancer.
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This study aims to assess the impact of a computerised cognitive training program on the neurotoxic effects of chemotherapy on cognition in breast cancer patients.
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The purpose of this study is to determine if breast cancer genetic material (known as circulating tumour DNA (ctDNA) can be detected in the bloodstream. It is hoped that this research will demonstrate the utility of this circulating material as an early marker of residual or recurrent breast cancer activity after treatment
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An open-label, randomized, window of opportunity study between diagnosis and definite surgery, to assess the effect of antiestrogen therapies, alone and in combination with microionized progesterone (prometrium) in patients with newly diagnosed ER+PR+ breast cancer.
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This trial aims to determine feasibility and preliminary efficacy of a 12-week online yoga program in women with breast cancer-related lymphoedema, and to evaluate its impact on coping skills and quality of life.
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The purpose of this study is to determine the effect of an online yoga exercise on mental health in women diagnosed with breast or gynaecological cancer.
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This study examines the impact of a fertility decision aid developed using health literacy principles on decision-related outcomes in younger women with breast cancer.
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